Dr. Honarmandi conducts biomimetic research to identify, address, and shed light on human problems. He uses his solid mechanics and design expertise for bioengineering applications. For example, he has used inspiration from the cushion-like microstructure between the skull and brain to propose a design for a new generation of helmets to better protect the head against impacts.
Another avenue of research for Dr. Honarmandi is computational and experimental cell mechanics from the nano- to micro-scale. He studies focal adhesion structures and the role of mechanical signaling in the mechanotransduction of cells. His research focuses on identifying the effect of mechanical loadings, as a form of axial/shear stress or strain, on the physiological behavior of cells. He has also developed a fabrication process to produce single-crystal hydroxyapatite nanomaterials as an artificial bone substitute in different medical applications.
Dr. Honarmandi’s research activities are as follows:
Microstructural model for osteocyte mechanotransduction
Mechanosensory mechanism of endothelial cells
Cell adhesion materials and mechanotransduction at molecular and cellular level
Head concussion and brain injury against impact
Utilization of graphene as fiber reinforcement in composite materials
Design and analysis of microfluidic device to study the effect of growth hormone on cells
Reliability-based design optimization of structures with fatigue constraints
PostDoc., Massachusetts Institute of Technology
Ph.D., University of Toronto
M.S., Amirkabir (Polytechnic) University of Technology
B.S., Sharif University of Technology
ENGS 206: Statics
MECH 230: Solid Mechanics
MECH 231: Solid Mechanics Laboratory
MECH 323: Machine Design
MECH 401: Mechanical Engineering Design I (Senior Design I)
MECH 402: Mechanical Engineering Design II (Senior Design II)
P. Honarmandi, A.M. Sadegh, P.V. Cacallaro, “Modeling and Impact Analysis of Football Player Head with Helmet Toward Mitigating Brain Concussion”, ”, Int. Journal of Experimental and Computational Biomechanics, Vol. 3, No. 4, 2015.
C. R. Kothapalli and P. Honarmandi, “Theoretical and Experimental Quantification of the Role of Diffusive Chemogradients on Neuritogenesis Within Three-Dimensional Collagen Scaffolds”, ActaBiomaterialia, Vol. 10 (9): 3664–3674, 2014.
Y. Zeng , M. Waters , A. Andrews, P. Honarmandi, and John Tarbel et al., “Fluid Shear Stress induces the Clustering of Heparan Sulfate via Mobility of Glypican-1 in Lipid Rafts”, American Journal of Physiology - Heart and Circulatory Physiology, Vol. 305, No. H811-H820, 2013.
P. Honarmandi, D. B. Heidary, “Theoretical Study on Effective Design Parameters in Elevator Vibration”, TSEST - Transaction on Control and Mechanical System, Vol. 2, No. 12, 2013.
P. Honarmandi, H. Lee, M. J. Lang, and R. D. Kamm, “A Microfluidic System with Optical Laser Tweezers to Study Mechanotransduction and Focal Adhesion Recruitment”, Lab on Chip, 11(4): 684-694, 2011.
P. Honarmandi, J. W. Zu, and K. Behdinan, “Analytical Study and Design Characteristics of Scratch Drive Actuators”, Journal of Sensors & Actuators: A. Physical, 160: 116-124, 2010.
P. Honarmandi et al., “Milling Media Effects on Synthesis, Morphology and Structural Characteristics of Single-Crystal Hydroxyapatite Nanoparticles”, Advances in Applied Ceramics: Structural, Functional and Bioceramics, 109(2): 117-122, 2010.
B.N. Tabrizi, and P. Honarmandi et al., “Synthesis of Nanosize Single-Crystal Hydroxyapatite via Mechanochemical Method”, Materials Letters, 63(5): 543-546, 2009.
P. Honarmandi, J. W. Zu, and K. Behdinan, “Probabilistic-Based Design Optimization of Cantilever Beams under Fatigue Constraint”, AIAA Journal, 45(11): 2737-2746, 2007.
Sloboda, and P. Honarmandi, “Generalized Elasticity Method for Curved Beam Stress Analysis: Analytical and Numerical Comparisons for a Lifting Hook”, Mechanics Based Design of Structures and Machines, 35(3): 319-332, 2007.
P. Honarmandi, J.W. Zu, and K. Behdinan, “Elasto-Plastic Fatigue Life Improvement of Bolted Joints and Introducing FBI Method”, Mechanics Based Design of Structures & Machines. 33(4): 311-330, 2005.
Published in Refereed Conferences/Presentations
P. Honarmandi, A.M. Sadegh, P.V. Cacallaro, “Do American Football Helmets Protect Players Against Concussions?”, ASME International Mechanical Engineering Congress & Exposition - Biomedical & Biotechnology, IMECE2013-64893, 5 pages, San Diego, Nov 15-21, 2013.
P. Honarmandi, A.M. Sadegh, “Modeling and Impact Analysis of Football Helmets: Toward Mitigating mTBI”, ASME International Mechanical Engineering Congress & Exposition - Biomedical & Biotechnology, IMECE2012-87173, 9 pages, Houston, Nov 9-15, 2012.
P. Honarmandi, “Fabrication of Single-Crystal Nanospherical Hydroxyapatite Powder for Biomedical Applications”, Proceedings of ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology, NEMB2010-13326, Houston, Feb 7-10, 2010.
P. Honarmandi, P. Bransford, and R. D. Kamm, “Mechanical Properties of α-Helices Estimated Using Molecular Dynamics and Finite Element Simulations”, ASME International Mechanical Engineering Congress & Exposition - Computational Bio-fluid and Bio-structural Mechanics, IMECE2008-69058, 7 pages, Boston, Nov 1-6, 2008.
R. D. Kamm, P. Honarmandi, T. Kim, W. Hwang, H. Lee, P. Bransford, J. Ferrer, M. J. Lang, “Modeling Force Transmission at the Sub-Cellular Scale and Its Role in Intracellular Signaling”, 13th Pacific Symposium on Biocomputing, Hawaii, Jan 4-8, 2008.
P. Honarmandi, J. W. Zu, and K. Behdinan, “ Probabilistic Optimization of Structures with Fatigue Constraint”, 21st Canadian Congress of Applied Mechanics, CANCAM 2007 Proceedings, pp. 91-93, Toronto, June 3-7, 2007.
A. Sloboda, and P. Honarmandi, “Analytical and Numerical Methods of Lifting Hook Stress Analysis”, 21st Canadian Congress of Applied Mechanics, CANCAM 2007 Proceedings, pp. 690-692, Toronto, June 3-7, 2007.
P. Honarmandi, J. W. Zu, and K. Behdinan, “Modeling and Analytical Study of Scratch Drive Actuators”, ASME International Mechanical Engineering Congress & Exposition – MEMS: Design, Dynamics and Controls of Micro/Nano Systems, IMECE2006-15379, 8 pages, Chicago, Nov 5-10, 2006.
P. Honarmandi, J. W. Zu, and K. Behdinan, “Reliability-Based Design Optimization of Cantilever Beams Under Fatigue Constraint”, 47th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference, AIAA-2006-1941, Newport, Rhode Island, 13 pages, May 1-4, 2006.
P. Honarmandi, J. W. Zu, K. Behdinan, and C. Park “Fatigue Life Improvement of the Bolt-Nut Joints using Axiomatic Design and FEM Approach”, Proceedings of the CSME Forum 2004, 1: 181-189, London, Ontario, June 1st-4th, 2004.
P. Honarmandi, J. W. Zu, and K. Behdinan, “Single-Axial Fatigue Analysis of the Automotive Front Door Hinge Assembly Based on FEM”, 19th Canadian Congress of Applied Mechanics, CANCAM 2003 Proceedings, 2: 252-254, Calgary, June 1-6, 2003.